‘The Elixir of Youth’? Omega-3s linked to youthful ‘organic age’



Telomeres, DNA sequences on the finish of chromosomes that shorten as cells replicate and age, doesn’t at all times correlate with chronological age, and there’s proof to counsel telomere shortening could also be modifiable by way of life elements.

“The elements which are strongly related to accelerated telomere shortening and dysfunction are oxidative stress and irritation,” ​defined scientists from Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences in Vitamins​.

“The power of omega‐3 fatty acids to scale back these damaging results is said not solely to their effectively‐documented useful impact on quite a few ‘way of life’ ailments but additionally to their useful results on telomere biology.

“The usage of omega‐3 fatty acids to scale back accelerated telomere attrition and, consequently, counteract untimely getting older and cut back the danger of age‐associated ailments raises excessive hopes.”

Telomeres

The getting older and lifespan of regular, wholesome cells are linked to the so-called telomerase shortening mechanism, which limits cells to a set variety of divisions. Throughout cell replication, the telomeres perform by guaranteeing the cell’s chromosomes don’t fuse with one another or rearrange, which might result in most cancers.

Elizabeth Blackburn, a telomere pioneer on the College of California San Francisco, likened telomeres to the ends of shoelaces, with out which the lace would unravel.

With every replication the telomeres shorten, and when the telomeres are completely consumed, the cells are destroyed (apoptosis). Telomere shortening or attrition was listed as one of many 9 hallmarks of getting older in a seminal paper printed in Cell​ in 2013 by Carlos López-Otín et al​.

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